Researchers from the Peter Doherty Institute for Infection and Immunity have developed a technique to render the HIV virus visible, aiding future treatment efforts. By using messenger RNA encapsulated in lipid nanoparticles (LNPs), the team was able to instruct cells to reveal the presence of the dormant virus in white blood cells. This breakthrough, which was once deemed impossible, allows the possibility of targeting the virus for elimination. Despite this progress, uncertainties remain regarding the immune system's response to the visible virus and further challenges in finding a definitive cure.
"Our hope is that this new nanoparticle design could be a new pathway to an HIV cure," she added.
"We were overwhelmed by how [much of a] night and day difference it was - from not working before, and then all of a sudden it was working. And all of us were just sitting gasping like, 'wow,'" Cevaal told the Guardian.
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