"Investigators at Weill Cornell Medicine and Cornell's Ithaca campus have received a three-year, $5.1 million grant from the National Institutes of Health's Autism Data Science Initiative (ADSI) to launch the Autism Replication, Validation, and Reproducibility (AR²) Center. The center aims to improve the reliability of autism research and foster public trust in the field."
""The AR2 Center will serve as a scientific quality control hub for the ADSI teams and projects," said the principal investigator, , chief of the Division of Biostatistics in the Department of Population Health Sciences and director of the Data Coordinating Center at Weill Cornell Medicine."
"Zhong and her colleagues will use a three-step process that starts with replicating the data analysis to confirm the initial results reported by ADSI investigators. Then, they will validate that the investigators' models work in different subsets of patients or in patients identified using different diagnostic tools. Finally, they will ensure that other scientists can reproduce the findings by providing adequate documentation and transparency."
A three-year, $5.1 million NIH ADSI grant established the Autism Replication, Validation, and Reproducibility (AR2) Center at Weill Cornell Medicine and Cornell's Ithaca campus. The center will act as a scientific quality-control hub to improve the reliability of autism research and foster public trust. AR2 will use existing data sources, including previous research datasets, Medicaid claims, and the INSIGHT Clinical Research Network, to assess validity and generalizability of findings. The team will replicate initial analyses, validate models across patient subsets and diagnostic tools, and ensure reproducibility through documentation and transparency. A community advisory board will include policymakers, researchers, and parents.
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