Psychedelics, Creativity, and Psychotropic Effects
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Psychedelics, Creativity, and Psychotropic Effects
"Creativity [is] broadly defined as the ability to generate novel and valuable ideas... [I]t includes problem-solving, shifting perspectives, and even deep personal transformation.... These substances appear to foster creativity by enhancing cognitive flexibility and breaking free from conventional thought patterns. The authors review neuroimaging research that demonstrates the ability of psychedelics to reset the connections between brain networks, especially the default mode network (DMN),"
""a brain network involved in introspection and self-referential thinking.... By altering patterns of brain activity and loosening cognitive constraints, they [psychedelics] may help restructure the creative process itself-opening pathways to original, unconventional, and enduring forms of expression.""
"By temporarily disconnecting specific brain networks, psychedelics may enhance creative thinking. Psychedelics may also promote reprogramming of rigid, unhealthy thoughts and behaviors. This characteristic of psychedelics might be helpful in treating several psychiatric illnesses. The benefits and risks of these powerful drugs must be carefully evaluated."
Psychedelics can enhance creative thinking by increasing cognitive flexibility and loosening conventional thought patterns. Neuroimaging evidence indicates psychedelics can reset connectivity among brain networks, notably altering the default mode network involved in introspection and self-referential thinking. Classic psychedelics such as LSD and psilocybin primarily stimulate serotonin 2A receptors, while non-classical agents like ketamine affect NMDA glutamate receptors. Psychedelics may enable reprogramming of rigid, unhealthy thoughts and behaviors, offering potential therapeutic effects for depression, anxiety, and substance use disorders. Careful evaluation of benefits, risks, dosing, and clinical protocols is required before wider therapeutic or cognitive use.
Read at Psychology Today
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