#genetic-variants

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#genomics #gene-regulation #massively-parallel-reporter-assays #computational-biology #human-evolution
#genomics
fromNature
1 week ago
Science

These powerful tools reveal the 'control knobs' of the genome

Most of the genome is not protein-coding and lacks a known regulatory code, so gene control is being decoded using massively parallel reporter assays.
fromNature
10 months ago
Parenting

Fetal and parental genomes offer mechanistic insights into pregnancy loss

Genetic analysis of pregnancy loss reveals that chromosomal abnormalities and subtle variants significantly contribute to early pregnancy loss in many cases.
Science
fromNature
1 week ago

These powerful tools reveal the 'control knobs' of the genome

Most of the genome is not protein-coding and lacks a known regulatory code, so gene control is being decoded using massively parallel reporter assays.
more#genomics
Medicine
fromNature
4 weeks ago

Landmark ancient-genome study shows surprise acceleration of human evolution

Human evolution has accelerated over the past 10,000 years, with significant gene variants identified in ancient populations from western Eurasia.
Medicine
fromNature
1 month ago

Saturation editing of RNU4-2 reveals distinct dominant and recessive disorders - Nature

De novo variants in RNU4-2 cause ReNU syndrome, a neurodevelopmental disorder characterized by developmental delays and other severe symptoms.
fromPsychology Today
4 months ago

How Mental Illness Leaves Its Mark on the Brain

Yet these experiences do not float free of the body. They are grounded in the brain itself. With its folds, ridges, and layers, the brain carries both the machinery of thought and the marks of our genetic inheritance. A new study shows just how deeply the two are connected. The very genes that increase vulnerability to psychiatric disorders also help shape the brain's physical architecture.
Psychology
Mental health
fromwww.theguardian.com
7 months ago

Women carry a higher genetic risk of depression, new study says

Females carry a higher genetic burden for major depression, with more sex-specific genetic variants and stronger genetic links to metabolic traits than males.
Science
fromInfoQ
10 months ago

Google DeepMind Unveils AlphaGenome: A Unified AI Model for High-Resolution Genome Interpretation

AlphaGenome is a new AI model that predicts the effect of genetic variants on gene regulation across the genome.
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