A group of scientists monitored 92 people with diabetes in Japan during their first year of treatment with weight-loss drugs and discovered that the patient's psychology can affect the success of these therapies. People who overate at the sight or smell of tasty food were more likely to respond well to the drugs over the long term, while those who overate for emotional reasons were less likely to do so.
"The drug also lowered patients' blood sugar levels by 1.3% on average, while the overall efficacy of orforglipron in promoting weight loss and controlling diabetes has been met with enthusiasm."