#t-cell-exhaustion
#t-cell-exhaustion

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Atlas-guided discovery of transcription factors for T cell programming - Nature

Transcription factors determine CD8+ T cell states; identifying TFs that promote tissue-resident memory versus terminal exhaustion enables engineering of more effective adoptive T cell therapies.

Medicine

fromNature

4 months ago

Proteotoxic stress response drives T cell exhaustion and immune evasion - Nature

Proteomic profiling of exhausted T cells reveals pathway-specific transcript–protein discordance and identifies T cell–exhaustion-specific protein-level regulatory mechanisms.

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#t-cell-exhaustion#t-cell-exhaustion

Atlas-guided discovery of transcription factors for T cell programming - Nature

Proteotoxic stress response drives T cell exhaustion and immune evasion - Nature

#t-cell-exhaustion
#t-cell-exhaustion