The article addresses a letter from an individual struggling with the long-term effects of antidepressants on their sex life. After nearly 25 years on medication, the writer feels detached from sexual desire and grapples with the impact on their marriage. While the wife's sympathy lies in her understanding of the pharmacology, she also seeks a fulfilling sex life. The response emphasizes exploring all antidepressant options under a psychiatrist's guidance, suggesting that tailored support could help improve their situation.
"Before we dig in, I want to make sure that you've tried—under the supervision of an actual psychiatrist—all the antidepressants available to you."
"Neither of us is OK with an open relationship. Help?"
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