SciencefromNature2 weeks agoEngineered prime editors with minimal genomic errors - NaturePrime editors enable programmed DNA replacement via Cas9 nickase–RT and pegRNAs, but indel byproducts from scaffold extension and DSBs remain a major challenge.
MedicinefromNature4 months agoWorld first: ultra-powerful CRISPR treatment trialled in a personPrime editing has been used successfully in a patient for the first time, offering hope for rare disease treatments.